AS primarily affects the spine and sacroiliac joints, usually starting in young adults. Rheumatoid Arthritis commonly affects the small joints of the hands and feet. AS is also more associated with HLA-B27 positivity and spinal fusion.

Diagnosis is based on symptoms (like chronic back pain and stiffness), physical examination, imaging tests (X-ray or MRI of the spine and sacroiliac joints), and blood tests including HLA-B27 and inflammatory markers (ESR, CRP).

No. HLA-B27 positivity increases the risk of developing AS, but not everyone with the gene will develop the disease. A proper diagnosis depends on symptoms, physical findings, and imaging.

AS is a long-term condition that varies from person to person. In some, it remains mild, while in others it can cause severe spinal stiffness, reduced mobility, and complications involving the eyes, heart, or lungs if not managed properly.

There is no permanent cure, but with early diagnosis and appropriate treatment, symptoms can be well managed, and long-term complications can often be prevented or minimized.

Treatment includes anti-inflammatory medications, biologics (like TNF inhibitors), regular exercise, posture management, and in rare cases, surgery. Early treatment improves quality of life and slows progression.

Yes. Physiotherapy and regular exercise are key parts of AS treatment. They help maintain flexibility, improve posture, reduce stiffness, and prevent spinal fusion.

Yes, you can plan a family. While AS has a genetic component, not all children will inherit or develop the condition. It’s advised to discuss family planning with your rheumatolo

Currently, stem cell therapy is not a recommended or proven treatment for AS. Evidence-based medications and therapies remain the best options for managing the disease.

Yes. Smoking worsens AS symptoms, speeds up disease progression, and reduces the effectiveness of medications. Quitting smoking is highly recommended for better disease control.